Grhl2 - grainyhead-like transcription factor 2 Gene

Predicted to enable DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in several processes, including epithelial cell differentiation; nervous system development; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within several processes, including animal organ development; embryonic morphogenesis; and face development. Predicted to be located in cell-cell junction and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4. Orthologous to human GRHL2 (grainyhead like transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]