Nelfa - negative elongation factor complex member A Gene

Also Known as Whsc2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 305455

Summary

Enables chromatin binding activity. Involved in positive regulation of histone H3-K4 methylation and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nuclear body. Predicted to be part of NELF complex. Orthologous to human NELFA (negative elongation factor complex member A). [provided by Alliance of Genome Resources, Apr 2022]

Nelfa Products (1)

mRNA Protein Name
NM_001008339.1 NP_001008340.1 negative elongation factor A

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IMP
IMP: Inferred from mutant phenotype
21623364 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of protein modification process IMP
IMP: Inferred from mutant phenotype
21623364 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21623364 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

negative elongation factor A

  • Wolf-Hirschhorn syndrome candidate 2 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09201 NELFA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21664 Nelfa Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28182 Nelfa Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nelfa NCBI NCBI:7469