Pde12 - phosphodiesterase 12 Gene

Also Known as 2-PDE; 2'-PDE; LRRGT00074; RGD1310975

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 306231

About Pde12

Primary_assembly 16: 1,915,386-1,925,887 reverse strand.mRatBN7.2:CM026989.1

This gene has 2 transcripts (splice variants), 204 orthologues, 5 paralogues and is associated with 2 phenotypes. Biased expression in Kidney (RPKM 17.6), Thymus (RPKM 84.7) and 9 other tissues.

Summary

Predicted to enable 3'-5'-exoribonuclease activity. Predicted to be involved in several processes, including RNA metabolic process; cellular response to cytokine stimulus; and regulation of mitochondrial mRNA stability. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human PDE12 (phosphodiesterase 12). [provided by Alliance of Genome Resources, Apr 2022]

Pde12 Products (1)

mRNA Protein Name
NM_001411708.1 NP_001398637.1 2',5'-phosphodiesterase 12
Protein Preferred Names Protein Names

2',5'-phosphodiesterase 12

  • mitochondrial deadenylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-117318 PDE12-IN-1 Inhibitor 99.11% Unkown
HY-124768 PDE12-IN-3 Inhibitor 98.02% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pde12 NCBI NCBI:201626