Tfap2a - transcription factor AP-2 alpha Gene

Also Known as Tcfap2a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 306862

Summary

Enables sequence-specific DNA binding activity. Involved in several processes, including Schwann cell development; response to lipopolysaccharide; and response to water deprivation. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in branchiooculofacial syndrome. Orthologous to human TFAP2A (transcription factor AP-2 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Tfap2a Products (1)

mRNA Protein Name
NM_001107345.2 NP_001100815.1 transcription factor AP-2-alpha

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17762867 RGD
Biological Process GO Annotation Evidence References Source
involved in Schwann cell development IEP
IEP: Inferred from expression pattern
11553286 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21039521 RGD
involved in response to lipopolysaccharide IDA
IDA: Inferred from direct assay
11688998 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor AP-2-alpha

  • AP-2 transcription factor

  • AP2-alpha

  • activating enhancer-binding protein 2-alpha

  • activator protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14408 TFAP2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19271 Tfap2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25760 Tfap2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tfap2a NCBI NCBI:7020