Smpd1 - sphingomyelin phosphodiesterase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 308909

Summary

Predicted to enable acid sphingomyelin phosphodiesterase activity and zinc ion binding activity. Involved in several processes, including ceramide biosynthetic process; positive regulation of apoptotic process; and response to cocaine. Located in extracellular space and lamellar body. Used to study Wilson disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease; Niemann-Pick disease type A; and Niemann-Pick disease type B. Orthologous to human SMPD1 (sphingomyelin phosphodiesterase 1). [provided by Alliance of Genome Resources, Apr 2022]

Smpd1 Products (1)

mRNA Protein Name
NM_001006997.1 NP_001006998.1 sphingomyelin phosphodiesterase
Protein Preferred Names Protein Names

sphingomyelin phosphodiesterase

  • sphingomyelin phosphodiesterase 1, acid lysosomal

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS17994 Smpd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-134505 Avicin G Inhibitor / Unkown
HY-186165 KARI 101 / Unkown
HY-RS13447 SMPD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24465 Smpd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smpd1 NCBI NCBI:6609
Mus musculus Smpd1 NCBI NCBI:20597