Hacd1 - 3-hydroxyacyl-CoA dehydratase 1 Gene

Also Known as Ptpla

Species: Mus musculus

Gene Type: protein coding
Gene ID: 30963

Summary

Predicted to enable enzyme binding activity; hydro-lyase activity; and hydroxyapatite binding activity. Acts upstream of or within myotube differentiation; regulation of G1/S transition of mitotic cell cycle; and regulation of G2/M transition of mitotic cell cycle. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; embryo mesenchyme; ganglia; musculature; and vibrissa follicle. Orthologous to human HACD1 (3-hydroxyacyl-CoA dehydratase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hacd1 Products (2)

mRNA Protein Name
NM_001012396.2 NP_001012396.2 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 isoform 2
NM_013935.3 NP_038963.3 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within myotube differentiation IGI
IGI: Inferred from genetic interaction
22106411 MGI
acts upstream of or within regulation of G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
22106411 MGI
acts upstream of or within regulation of G2/M transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
22106411 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1

  • protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a

  • protein-tyrosine phosphatase-like member A

  • very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05984 HACD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22545 Hacd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29065 Hacd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hacd1 NCBI NCBI:9200