Kif5c - kinesin family member 5C Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 311024

Summary

Enables ATP hydrolysis activity; Apolipoprotein receptor binding activity; and microtubule binding activity. Involved in ATP metabolic process; anterograde axonal protein transport; and anterograde dendritic transport of messenger ribonucleoprotein complex. Located in dendrite. Human ortholog(s) of this gene implicated in complex cortical dysplasia with Other brain malformations 2 and schizophrenia. Orthologous to human KIF5C (Kinesin family member 5C). [provided by Alliance of Genome Resources, Apr 2022]

Kif5c Products (1)

mRNA Protein Name
NM_001107730.1 NP_001101200.1 kinesin heavy chain isoform 5C

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP hydrolysis activity IDA
IDA: Inferred from direct assay
7602588 RGD
enables apolipoprotein receptor binding IPI
IPI: Inferred from physical interaction
11238452 RGD
enables microtubule binding IDA
IDA: Inferred from direct assay
7602588 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
19135897 RGD
Biological Process GO Annotation Evidence References Source
involved in anterograde axonal protein transport IMP
IMP: Inferred from mutant phenotype
23576431 RGD
involved in intracellular mRNA localization IMP
IMP: Inferred from mutant phenotype
23121659 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
20152113 RGD
located in dendrite IDA
IDA: Inferred from direct assay
22355657 RGD
is active in postsynaptic cytosol IDA
IDA: Inferred from direct assay
20152113 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kinesin heavy chain isoform 5C

  • kinesin heavy chain neuron-specific 2

  • kinesin-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07291 KIF5C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22598 Kif5c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29115 Kif5c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kif5c NCBI NCBI:3800