Mad2l2 - mitotic arrest deficient 2 like 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 313702

Summary

Predicted to enable JUN kinase binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including negative regulation of cell-cell adhesion mediated by cadherin; regulation of nucleobase-containing compound metabolic process; and regulation of protein metabolic process. Predicted to be located in cytosol; nucleolus; and spindle. Predicted to be part of zeta DNA Polymerase complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group V. Orthologous to human MAD2L2 (mitotic arrest deficient 2 like 2). [provided by Alliance of Genome Resources, Apr 2022]

Mad2l2 Products (2)

mRNA Protein Name
NM_001012106.2 NP_001012106.1 mitotic spindle assembly checkpoint protein MAD2B isoform 2
NM_001394241.1 NP_001381170.1 mitotic spindle assembly checkpoint protein MAD2B isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
27488450 RGD
involved in positive regulation of extracellular matrix assembly IMP
IMP: Inferred from mutant phenotype
27488450 RGD
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
27488450 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitotic spindle assembly checkpoint protein MAD2B

  • MAD2 mitotic arrest deficient-like 2

  • MAD2-like protein 2

  • mitotic arrest deficient 2-like protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07951 MAD2L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19788 Mad2l2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26284 Mad2l2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mad2l2 NCBI NCBI:10459