Itga5 - integrin subunit alpha 5 Gene

Also Known as Itga5_retired

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 315346

Summary

Enables epidermal growth factor receptor binding activity and Integrin binding activity. Involved in several processes, including female pregnancy; integrin-mediated signaling pathway; and positive regulation of cell-substrate adhesion. Located in cytoplasm. Part of Integrin complex. Orthologous to human ITGA5 (Integrin subunit alpha 5). [provided by Alliance of Genome Resources, Apr 2022]

Itga5 Products (1)

mRNA Protein Name
NM_001108118.1 NP_001101588.1 integrin alpha-5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cell adhesion molecule binding IDA
IDA: Inferred from direct assay
12821041 RGD
enables epidermal growth factor receptor binding IPI
IPI: Inferred from physical interaction
21349584 RGD
enables integrin binding IPI
IPI: Inferred from physical interaction
18167060 RGD
Biological Process GO Annotation Evidence References Source
involved in cell adhesion IDA
IDA: Inferred from direct assay
12821041 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
17715430 RGD
involved in integrin-mediated signaling pathway IDA
IDA: Inferred from direct assay
12821041 RGD
involved in positive regulation of cell migration IMP
IMP: Inferred from mutant phenotype
18167060 RGD
involved in positive regulation of cell-substrate adhesion IMP
IMP: Inferred from mutant phenotype
18167060 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27518800 RGD
part of integrin complex IDA
IDA: Inferred from direct assay
12821041 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
27518800 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin alpha-5

  • integrin alpha 5 (fibronectin receptor alpha)

  • integrin, alpha 5 (fibronectin receptor, alpha polypeptide)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06952 ITGA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16901 Itga5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23343 Itga5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itga5 NCBI NCBI:3678