HTR5A - 5-hydroxytryptamine receptor 5A Gene

Homo sapiens

Also known as 5-HT5A

Gene ID: 3361 | Gene type: protein coding

About HTR5A

Cytogenetic location: 7q36.2 Genomic coordinates (GRCh38): 7:155,070,324-155,087,392 (from NCBI)

This gene has 3 transcripts (splice variants), 215 orthologues and 8 paralogues. Restricted expression toward brain (RPKM 2.3).

Summary

The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]

HTR5A Products(1)

mRNA	Protein	Name
NM_024012.4	NP_076917.1	5-hydroxytryptamine receptor 5A

HTR5A Protein Structure

7tm_1

0
100
200
300
357 a.a.

Protein Preferred Names

Protein Names

5-hydroxytryptamine receptor 5A

5-HT-5	5-HT-5A
5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

Related Diseases

Diseases

Alias

Sacral Defect With Anterior Meningocele

Caudal Regression Syndrome	Caudal Regression Sequence
Sacral Agenesis	Caudal Dysgenesis Syndrome
SDAM	Caudal Dysplasia Sequence
Caudal Dysplasia	Sacral Agenesis Syndrome
Sacral Regression Syndrome	Sacral Defect And Anterior Sacral Meningocele
Rudd Klimek Syndrome	Sirenomelia

Ciliary Dyskinesia, Primary, 19

Primary Ciliary Dyskinesia 19	CILD19
Primary Ciliary Dyskinesia 19 With Or Without Situs Inversus	Ciliary Dyskinesia, Primary, 19, With Or Without Situs Inversus
Ics19	Immotile Cilia Syndrome 19
Dyskinesia, Ciliary, Primary, 19

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS06477	HTR5A Human Pre-designed siRNA Set A	/	Unkown
HY-RS06478	Htr5a Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS06479	Htr5a Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	HTR5A	MGD	MGI:96283
Canis familiaris	HTR5A	VGNC	VGNC:41832
Bos taurus	HTR5A	VGNC	VGNC:30001
Macaca mulatta	HTR5A	VGNC	VGNC:73545
Felis catus	HTR5A	VGNC	VGNC:102598
Rattus norvegicus	HTR5A	RGD	RGD:2851

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