RAB43 - RAB43, member RAS oncogene family Gene
Also Known as RAB41; RAB11B
Species: Homo sapiens
About RAB43
This gene has 8 transcripts (splice variants), 144 orthologues and 68 paralogues. Ubiquitous expression in thyroid (RPKM 20.1), lung (RPKM 12.9) and 25 other tissues.
Summary
Enables GTPase activity. Involved in several processes, including Golgi organization; phagosome maturation; and retrograde transport, plasma membrane to Golgi. Located in Golgi apparatus and phagocytic vesicle. [provided by Alliance of Genome Resources, Apr 2022]
RAB43 Products (7)
| mRNA | Protein | Name |
|---|---|---|
| NM_001204883.2 | NP_001191812.1 | ras-related protein Rab-43 isoform a |
| NM_001204884.2 | NP_001191813.1 | ras-related protein Rab-43 isoform a |
| NM_001204885.1 | NP_001191814.1 | ras-related protein Rab-43 isoform a |
| NM_001204886.2 | NP_001191815.1 | ras-related protein Rab-43 isoform a |
| NM_001204887.2 | NP_001191816.1 | ras-related protein Rab-43 isoform b |
| NM_001204888.2 | NP_001191817.1 | ras-related protein Rab-43 isoform c |
| NM_198490.3 | NP_940892.1 | ras-related protein Rab-43 isoform a |
RAB43 Protein Structure
Ras: Ras family (20 - 180)
- 0
- 100
- 200
- 212 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ras-related protein Rab-43 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Smith-Mccort Dysplasia 1 |
|
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| Dyggve-Melchior-Clausen Disease |
|
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | RAB43 | VGNC | VGNC:45289 |
| Mus musculus | RAB43 | MGD | MGI:1917084 |
| Rattus norvegicus | RAB43 | RGD | RGD:1565300 |
| Felis catus | RAB43 | VGNC | VGNC:102700 |
| Others | RAB43 | NCBI |