Gtf2i - general transcription factor II I Gene

Also Known as Gtf2ird1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 353256

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II-specific DNA-binding transcription factor binding activity; and mitogen-activated protein kinase binding activity. Involved in negative regulation of cytosolic calcium ion concentration. Predicted to be located in cell projection; neuronal cell body; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human GTF2I (general transcription factor IIi). [provided by Alliance of Genome Resources, Apr 2022]

Gtf2i Products (3)

mRNA Protein Name
NM_001001512.3 NP_001001512.2 general transcription factor II-I isoform 1
NM_001401209.1 NP_001388138.1 general transcription factor II-I isoform 2
NM_001401210.1 NP_001388139.1 general transcription factor II-I isoform 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
17023658 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

general transcription factor II-I

  • GTFII-I

  • TFII-I

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05903 GTF2I Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20950 Gtf2i Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27467 Gtf2i Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gtf2i NCBI NCBI:2969