Brip1 - BRCA1 interacting helicase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360588

Summary

Enables chromatin binding activity. Involved in several processes, including cellular response to angiotensin; cellular response to hypoxia; and cellular response to vitamin. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group J; breast cancer; colorectal cancer; and thrombocytopenia. Orthologous to human BRIP1 (BRCA1 interacting helicase 1). [provided by Alliance of Genome Resources, Apr 2022]

Brip1 Products (1)

mRNA Protein Name
XM_006247063.4 XP_006247125.1 Fanconi anemia group J protein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
22212472 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to angiotensin IEP
IEP: Inferred from expression pattern
26503970 RGD
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
12511571 RGD
involved in cellular response to vitamin IEP
IEP: Inferred from expression pattern
16771696 RGD
involved in negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
16771696 RGD
involved in negative regulation of gene expression IDA
IDA: Inferred from direct assay
12511571 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
24243707 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Fanconi anemia group J protein

  • BRCA1 interacting protein C-terminal helicase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01623 BRIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20866 Brip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27381 Brip1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brip1 NCBI NCBI:83990