Spag9 - sperm associated antigen 9 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360600

Summary

Predicted to enable several functions, including Kinesin binding activity; protein kinase binding activity; and signaling adaptor activity. Involved in negative regulation of dendrite extension; negative regulation of neuron differentiation; and negative regulation of protein phosphorylation. Predicted to be located in several cellular components, including centriolar satellite; lysosomal membrane; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and liver cirrhosis. Orthologous to human SPAG9 (sperm associated antigen 9). [provided by Alliance of Genome Resources, Apr 2022]

Spag9 Products (1)

mRNA Protein Name
NM_001108290.2 NP_001101760.2 C-Jun-amino-terminal kinase-interacting protein 4

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of dendrite extension IMP
IMP: Inferred from mutant phenotype
19959466 RGD
involved in negative regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
19959466 RGD
involved in negative regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
19959466 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-Jun-amino-terminal kinase-interacting protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13627 SPAG9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22820 Spag9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29335 Spag9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spag9 NCBI NCBI:9043