Sucla2 - succinate-CoA ligase ADP-forming subunit beta Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361071

Summary

Enables succinate-CoA Ligase (ADP-forming) activity. Involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 5. Orthologous to human SUCLA2 (succinate-CoA Ligase ADP-forming subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Sucla2 Products (1)

mRNA Protein Name
NM_001108387.2 NP_001101857.2 succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables succinate-CoA ligase (ADP-forming) activity IDA
IDA: Inferred from direct assay
17403370 RGD
Biological Process GO Annotation Evidence References Source
involved in succinate metabolic process IDA
IDA: Inferred from direct assay
17403370 RGD
involved in succinyl-CoA metabolic process IDA
IDA: Inferred from direct assay
17403370 RGD
involved in tricarboxylic acid cycle IDA
IDA: Inferred from direct assay
17403370 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

  • succinate-CoA ligase ADP-forming beta subunit

  • succinate-CoA ligase beta subunit

  • succinate-Coenzyme A ligase, ADP-forming, beta subunit

  • succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14000 SUCLA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21951 Sucla2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28468 Sucla2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sucla2 NCBI NCBI:8803