Lamtor3 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 Gene

Also Known as MP1; Mapksp1; Map2k1ip1

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 362045

Summary

Predicted to enable kinase activator activity. Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in cellular protein localization; cellular response to amino acid stimulus; and positive regulation of TOR signaling. Predicted to act upstream of or within positive regulation of MAPK cascade and protein localization to cell junction. Predicted to be located in late endosome. Predicted to be part of Ragulator complex. Orthologous to human LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and mTOR Activator 3). [provided by Alliance of Genome Resources, Apr 2022]

Lamtor3 Products (1)

mRNA	Protein	Name
NM_001008375.1	NP_001008376.1	ragulator complex protein LAMTOR3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	19177150	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
ragulator complex protein LAMTOR3	MEK partner 1 late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 mitogen-activated protein kinase kinase 1-interacting protein 1 mitogen-activated protein kinase scaffold protein 1

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07515	LAMTOR3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS19090	Lamtor3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS25580	Lamtor3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lamtor3	NCBI	NCBI:8649