Impdh1 - inosine monophosphate dehydrogenase 1 Gene

Also Known as IMPD 1; IMPDH 1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362329

Summary

Predicted to enable DNA binding activity; IMP dehydrogenase activity; and identical protein binding activity. Involved in response to cold and retina development in camera-type eye. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 11; retinitis pigmentosa; and retinitis pigmentosa 10. Orthologous to human IMPDH1 (inosine monophosphate dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Impdh1 Products (2)

mRNA Protein Name
NM_001108619.1 NP_001102089.1 inosine-5'-monophosphate dehydrogenase 1 isoform 1
NM_001398857.1 NP_001385786.1 inosine-5'-monophosphate dehydrogenase 1 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in retina development in camera-type eye IEP
IEP: Inferred from expression pattern
18295529 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inosine-5'-monophosphate dehydrogenase 1

  • IMP (inosine 5'-monophosphate) dehydrogenase 1

  • IMP (inosine monophosphate) dehydrogenase 1

  • IMP dehydrogenase 1

  • inosine 5'-phosphate dehydrogenase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-118917 VX-148 Inhibitor / Unkown
HY-147342 β-Benzamide adenine dinucleotide Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Impdh1 NCBI NCBI:3614