Car12 - carbonic anhydrase 12 Gene

Also Known as Ca12

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363085

About Car12

Primary_assembly 8: 67,274,359-67,330,440 forward strand.mRatBN7.2:CM026981.1

This gene has 3 transcripts (splice variants), 215 orthologues, 16 paralogues and is associated with 6 phenotypes.

Summary

Predicted to enable carbonate dehydratase activity. Predicted to be involved in chloride ion homeostasis and one-carbon metabolic process. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in isolated hyperchlorhidrosis. Orthologous to human CA12 (Carbonic Anhydrase 12). [provided by Alliance of Genome Resources, Apr 2022]

Car12 Products (1)

mRNA Protein Name
NM_001080756.2 NP_001074225.1 carbonic anhydrase 12 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in estrous cycle IEP
IEP: Inferred from expression pattern
23869188 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
23869188 RGD
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
12923247 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carbonic anhydrase 12

  • carbonic anyhydrase 12

  • membrane-bound carbonic anhydrase 12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01907 Car12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01908 Car12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown