NDP - Ndp norrin cystine knot growth factor NDP Gene

Also Known as Ndph; RGD1563968

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363443

Summary

Predicted to enable cytokine activity; Frizzled binding activity; and protein homodimerization activity. Involved in decidualization. Predicted to be located in cell surface; collagen-containing extracellular matrix; and extracellular space. Predicted to be active in extracellular matrix. Human ortholog(s) of this gene implicated in Norrie disease; X-linked exudative vitreoretinopathy 2; and retinopathy of prematurity. Orthologous to human NDP (norrin cystine knot growth factor NDP). [provided by Alliance of Genome Resources, Apr 2022]

NDP Products (1)

mRNA Protein Name
NM_001108814.1 NP_001102284.1 norrin precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in decidualization IEP
IEP: Inferred from expression pattern
21899531 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

norrin

  • NDP, norrin cystine knot growth factor

  • Norrie disease (pseudoglioma)

  • Norrie disease homolog

  • norrin-like

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-107139 JNJ-10229570 Antagonist 98.0% Phase 2

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-113206A D-Sedoheptulose-7-phosphate barium 99.70% Unkown
HY-P2881 Nucleoside diphosphate kinase / Unkown
HY-113206 D-Sedoheptulose 7-phosphate ≥98.0% Unkown
HY-E70122 Uridylate kinase / Unkown
HY-121183 Aprikalim Activator / Unkown
HY-RS09113 NDP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19302 Ndp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25793 Ndp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens NDP NCBI NCBI:4693