Arl6 - ADP-ribosylation factor like GTPase 6 Gene

Predicted to enable GTP binding activity. Predicted to be involved in several processes, including cilium assembly; intracellular protein transport; and protein localization to non-motile cilium. Predicted to act upstream of or within several processes, including fat cell differentiation; protein transport from ciliary membrane to plasma membrane; and retina layer formation. Predicted to be located in cilium; cytosol; and membrane. Predicted to be active in axoneme. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 1; Bardet-Biedl syndrome 3; and retinitis pigmentosa 55. Orthologous to human ARL6 (ADP ribosylation factor like GTPase 6). [provided by Alliance of Genome Resources, Apr 2022]