Sox4 - SRY-box transcription factor 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 364712

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and miRNA binding activity. Involved in response to hypoxia. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome and urinary bladder Cancer. Orthologous to human SOX4 (SRY-box transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Sox4 Products (1)

mRNA Protein Name
NM_001271205.1 NP_001258134.1 transcription factor SOX-4
Biological Process GO Annotation Evidence References Source
involved in response to hypoxia IDA
IDA: Inferred from direct assay
12011571 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor SOX-4

  • SRY (sex determining region Y)-box 4

  • SRY box 4

  • SRY-box containing gene 4

Orthologs Information

Species Symbol Source ID
Homo sapiens Sox4 NCBI NCBI:6659