FZD8 - Fzd8 frizzled class receptor 8 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 364754

Summary

Predicted to enable several functions, including PDZ domain binding activity; Wnt-activated receptor activity; and Wnt-protein binding activity. Predicted to be involved in canonical Wnt signaling pathway and non-canonical Wnt signaling pathway. Predicted to act upstream of or within several processes, including T cell differentiation in thymus; angiogenesis; and positive regulation of JUN kinase activity. Predicted to be located in Golgi apparatus. Predicted to be part of Wnt-Frizzled-LRP5/6 complex. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Orthologous to human FZD8 (Frizzled class receptor 8). [provided by Alliance of Genome Resources, Apr 2022]

FZD8 Products (1)

mRNA Protein Name
NM_001044251.2 NP_001037716.1 frizzled-8 precursor
Protein Preferred Names Protein Names

frizzled-8

  • frizzled family receptor 8

  • frizzled-8-like

  • fz-8

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99667 Ipafricept Inhibitor 99.80% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05184 FZD8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18477 Fzd8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24958 Fzd8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens FZD8 NCBI NCBI:8325