Cpn1 - carboxypeptidase N subunit 1 Gene

Also Known as Cpn

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 365466

Summary

Enables Carboxypeptidase activity. Involved in bradykinin catabolic process; proteolysis; and response to glucocorticoid. Located in extracellular space. Human ortholog(s) of this gene implicated in Carboxypeptidase N deficiency. Orthologous to human CPN1 (Carboxypeptidase N subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Cpn1 Products (1)

mRNA Protein Name
NM_053526.2 NP_445978.1 carboxypeptidase N catalytic chain precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables carboxypeptidase activity IDA
IDA: Inferred from direct assay
11021404 RGD
enables carboxypeptidase activity IMP
IMP: Inferred from mutant phenotype
11299220 RGD
Biological Process GO Annotation Evidence References Source
involved in bradykinin catabolic process IMP
IMP: Inferred from mutant phenotype
11299220 RGD
involved in protein catabolic process IDA
IDA: Inferred from direct assay
11021404 RGD
involved in response to glucocorticoid IDA
IDA: Inferred from direct assay
10485340 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
10485340 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carboxypeptidase N catalytic chain

  • carboxypeptidase N catalytic chain-like

  • carboxypeptidase N small subunit

  • carboxypeptidase N, polypeptide 1, 50kD

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03101 CPN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03103 CPNE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03435 CYP11B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17315 Cyp11b1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20260 Cpn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26768 Cpn1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cpn1 NCBI NCBI:1369