KCNG1 - potassium voltage-gated channel modifier subfamily G member 1 Gene
Also Known as K13; kH2; KCNG; KV6.1
Species: Homo sapiens
About KCNG1
This gene has 6 transcripts (splice variants), 197 orthologues and 31 paralogues. Biased expression in endometrium (RPKM 3.9), placenta (RPKM 2.0) and 11 other tissues.
Summary
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, Insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the Potassium Channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008]
KCNG1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_002237.4 | NP_002228.2 | potassium voltage-gated channel subfamily G member 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables potassium channel regulator activity |
IDA
IDA: Inferred from direct assay
|
19074135 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of voltage-gated potassium channel complex |
IDA
IDA: Inferred from direct assay
|
19074135 | GOA |
KCNG1 Protein Structure
BTB_2: BTB/POZ domain (65 - 164)
Ion_trans: Ion transport protein (270 - 456)
- 0
- 100
- 200
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- 513 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
potassium voltage-gated channel subfamily G member 1 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Coumarin Resistance |
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