Terc - telomerase RNA component Gene

Also Known as Tr

Species: Rattus norvegicus

Gene Type: ncRNA
Gene ID: 378461

Summary

Predicted to enable template for synthesis of G-rich strand of telomere DNA activity. Involved in negative regulation of cell differentiation. Predicted to be part of Telomerase holoenzyme complex. Human ortholog(s) of this gene implicated in autosomal dominant dyskeratosis congenita 1; cervix uteri carcinoma in situ; and prostate Cancer. Orthologous to human TERC (Telomerase RNA component). [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cell differentiation IMP
IMP: Inferred from mutant phenotype
16424384 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-137817 BCH001 Inhibitor 98.72% Unkown
HY-174537 Human TERT mRNA / Unkown
HY-RS16330 TERC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17417 Terc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23871 Terc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Terc NCBI NCBI:7012