PTEN - phosphatase and tensin homolog Gene

Also Known as MMAC1

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 403832

About PTEN

Primary_assembly 26: 39,359,407-39,447,189 forward strand.ROS_Cfam_1.0:CM025125.1

This gene has 2 transcripts (splice variants), 139 orthologues, 5 paralogues and is associated with 1 phenotype.

PTEN Products (1)

mRNA Protein Name
NM_001003192.1 NP_001003192.1 phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

PTEN Protein Structure

PTP_PTEN

PTP_PTEN: cd14509 (23 - 180)

PTEN_C2

PTEN_C2: pfam10409 (187 - 348)

  • 0
  • 100
  • 200
  • 300
  • 403 a.a.
Protein Preferred Names Protein Names

phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

  • homolog of human mutated in multiple advanced cancers

  • mutated in multiple advanced cancers 1

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-128932 Cefminox sodium 99.83% Unkown

Pre-clinical Phase

Bioactive Molecules (24)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13074 VO-Ohpic trihydrate Inhibitor / Unkown
HY-128693 BpV(HOpic) Inhibitor ≥98.0% Unkown
HY-15842 SF1670 Inhibitor 98.57% Unkown
HY-N1435 Oroxin B Activator 99.39% Unkown
HY-N0103 Sophocarpine Activator 99.85% Unkown
HY-N1441 Afzelin 99.62% Unkown
HY-160093 SQLE-IN-1 Inducer 99.21% Unkown
HY-136065 bpV(phen) Inhibitor 98.0% Unkown
HY-N2116 Ginkgolic acid C17:1 Inhibitor 99.80% Unkown
HY-144707 AK-778-XXMU Agonist 99.96% Unkown
HY-122818 BpV(phen) trihydrate Inhibitor 98.0% Unkown
HY-106263B Tyroserleutide hydrochloride Activator 99.92% Unkown
HY-18764 BpV(pic) potassium hydrate Inhibitor 98.8% Unkown
HY-N2993 Polyporenic acid C Activator ≥99.0% Unkown
HY-170791 CIB-L43 Activator 99.71% Unkown
HY-N11709 Theasaponin E1 Activator 98.68% Unkown
HY-N8884 Coelonin Inhibitor 98.0% Unkown
HY-N7325 Valerosidate Inducer 96% Unkown
HY-178360 NP1192 / Unkown
HY-181097 EGFR-IN-192 Modulator / Unkown
HY-110067 VO-OHPic Inhibitor / Unkown
HY-179498 ROCK2-IN-13 Activator / Unkown
HY-167843 Alborixin / Unkown
HY-131549A bpV(bipy) hydrate Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PTEN NCBI NCBI:5728