MUC3A - mucin 3A, cell surface associated Gene
Also Known as MUC3; MUC-3A
Species: Homo sapiens
About MUC3A
This gene has 4 transcripts (splice variants), 30 orthologues and 2 paralogues. Biased expression in duodenum (RPKM 17.8), small intestine (RPKM 15.8) and 6 other tissues.
Summary
The Mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 [PubMed 7778880]).[supplied by OMIM, Aug 2008]
MUC3A Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_005960.2 | NP_005951.1 | mucin-3A precursor |
MUC3A Protein Structure
SEA: SEA domain (576 - 667)
- 0
- 200
- 400
- 600
- 800
- 876 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
mucin-3A |
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Related Diseases
| Diseases | Alias | |
|---|---|---|
| Inflammatory Bowel Disease 11 |
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| Inflammatory Bowel Disease |
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| Bronchiolo-Alveolar Adenocarcinoma |
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| Vernal Conjunctivitis |
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| Lung Mucoepidermoid Carcinoma |
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| Colorectal Cancer |
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| Renal Cell Carcinoma, Nonpapillary |
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| Cystic Fibrosis |
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| Lung Cancer Susceptibility 3 |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | MUC3A | MGD | MGI:3588263 |
| Rattus norvegicus | MUC3A | RGD | RGD:41045133 |