HDAC11 - histone deacetylase 11 Gene
Species: Canis lupus familiaris (sub-species: familiaris)
Gene Type: protein coding
Gene ID: 484633
About HDAC11
Primary_assembly 20: 3,815,104-3,838,043 forward strand.ROS_Cfam_1.0:CM025119.1
This gene has 8 transcripts (splice variants), 198 orthologues and 10 paralogues.
HDAC11 Products (10)
| mRNA | Protein | Name |
|---|---|---|
| XM_038426814.1 | XP_038282742.1 | histone deacetylase 11 isoform X5 |
| XM_038426812.1 | XP_038282740.1 | histone deacetylase 11 isoform X4 |
| XM_038426817.1 | XP_038282745.1 | histone deacetylase 11 isoform X8 |
| XM_038426813.1 | XP_038282741.1 | histone deacetylase 11 isoform X4 |
| XM_038426818.1 | XP_038282746.1 | histone deacetylase 11 isoform X4 |
| XM_038426809.1 | XP_038282737.1 | histone deacetylase 11 isoform X1 |
| XM_038426810.1 | XP_038282738.1 | histone deacetylase 11 isoform X2 |
| XM_038426811.1 | XP_038282739.1 | histone deacetylase 11 isoform X3 |
| XM_038426815.1 | XP_038282743.1 | histone deacetylase 11 isoform X6 |
| XM_038426816.1 | XP_038282744.1 | histone deacetylase 11 isoform X7 |
HDAC11 Protein Structure
HDAC_classIV
HDAC_classIV: cd09993 (34 - 336)
- 0
- 100
- 200
- 300
- 365 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
histone deacetylase 11 |
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(7)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-10221 | Vorinostat | Inhibitor | 99.96% | Yes |
| HY-109015 | Tucidinostat | Inhibitor | 98.74% | Unkown |
| HY-12164 | Mocetinostat | Inhibitor | 99.68% | Yes |
| HY-14842 | Givinostat | Inhibitor | 98.67% | Yes |
| HY-13322 | Pracinostat | Inhibitor | 99.80% | Yes |
| HY-14842B | Givinostat hydrochloride monohydrate | Inhibitor | 99.63% | Yes |
| HY-14842A | Givinostat hydrochloride | Inhibitor | 98.06% | Yes |
Clinical Phase
Bioactive Molecules
(5)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-15433 | Quisinostat | Inhibitor | 99.71% | Phase 2 |
| HY-13522 | Fimepinostat | Inhibitor | 99.95% | Phase 2 |
| HY-15433A | Quisinostat dihydrochloride | Inhibitor | 99.05% | Phase 2 |
| HY-16012A | Domatinostat | Inhibitor | 99.34% | Phase 2 |
| HY-16012 | Domatinostat tosylate | Inhibitor | 99.66% | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(57)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-13428 | Tubacin | Inhibitor | 97.11% | Unkown |
| HY-18998 | LMK-235 | Inhibitor | 99.61% | Unkown |
| HY-112285 | FT895 | Inhibitor | 99.84% | Unkown |
| HY-128918 | SIS17 | Inhibitor | 99.43% | Unkown |
| HY-16699 | Nexturastat A | Inhibitor | 98.69% | Unkown |
| HY-145757 | Elevenostat | Inhibitor | 95.07% | Unkown |
| HY-115475 | SW-100 | Inhibitor | 99.93% | Unkown |
| HY-126330 | SS-208 | Inhibitor | 99.00% | Unkown |
| HY-150109 | Purinostat mesylate | Inhibitor | 99.45% | Unkown |
| HY-135714 | Bavarostat | Inhibitor | 99.51% | Unkown |
| HY-172157 | HDAC11-IN-2 | Inhibitor | 99.52% | Unkown |
| HY-176542 | TD034 | Inhibitor | 99.77% | Unkown |
| HY-143412 | MIR002 | Inhibitor | 99.0% | Unkown |
| HY-114483 | AES-135 | Inhibitor | 98.68% | Unkown |
| HY-143411 | GEM144 | Inhibitor | / | Unkown |
| HY-173444 | HDAC11-IN-3 | Inhibitor | 99.70% | Unkown |
| HY-110280 | MC1742 | Inhibitor | 98.95% | Unkown |
| HY-182019 | HDAC11-IN-5 | Inhibitor | / | Unkown |
| HY-138831 | AES-350 | Inhibitor | 99.30% | Unkown |
| HY-157740 | XSJ-10 | Inhibitor | 95.16% | Unkown |
| HY-178970 | HDAC11-IN-4 | Inhibitor | 95.0% | Unkown |
| HY-146684 | HDAC-IN-36 | Inhibitor | / | Unkown |
| HY-176868 | Rodin-C | Inhibitor | / | Unkown |
| HY-182717 | FT234 | Inhibitor | / | Unkown |
| HY-157481 | HDAC1-IN-6 | Inhibitor | / | Unkown |
| HY-179019 | HDAC-IN-94 | Inhibitor | / | Unkown |
| HY-162630 | HDAC6-IN-44 | Inhibitor | / | Unkown |
| HY-15144B | (S)-Trichostatin A | Inhibitor | / | Unkown |
| HY-150772 | Tubulin/HDAC-IN-1 | Inhibitor | / | Unkown |
| HY-152226 | MC2590 | Inhibitor | 98.71% | Unkown |
| HY-152225 | MC2625 | Inhibitor | / | Unkown |
| HY-180811 | ALK/HDAC-IN-2 | Inhibitor | / | Unkown |
| HY-143877 | NN-390 | Inhibitor | / | Unkown |
| HY-159171 | sEH/HDAC6-IN-2 | Inhibitor | / | Unkown |
| HY-184203 | SM-06-09 | Inhibitor | / | Unkown |
| HY-157889 | ZINC000028464438 | Inhibitor | / | Unkown |
| HY-181009 | HDAC-IN-98 | Inhibitor | 98.36% | Unkown |
| HY-163803 | CM-444 | Inhibitor | / | Unkown |
| HY-163207 | sEH/HDAC6-IN-1 | Inhibitor | / | Unkown |
| HY-152173 | HDAC-IN-51 | Inhibitor | / | Unkown |
| HY-15433B | Quisinostat hydrochloride | Inhibitor | / | Unkown |
| HY-183560 | HDAC6-IN-82 | Inhibitor | / | Unkown |
| HY-161350 | ALK/HDAC-IN-1 | Inhibitor | / | Unkown |
| HY-173076 | HDAC11-IN-1 | Inhibitor | / | Unkown |
| HY-161778 | ZG-126 | Inhibitor | / | Unkown |
| HY-180214 | HDAC6-IN-69 | Inhibitor | / | Unkown |
| HY-147966 | HDAC-IN-43 | Inhibitor | / | Unkown |
| HY-151263 | G4/HDAC-IN-1 | Inhibitor | / | Unkown |
| HY-162658 | Leuxinostat | Inhibitor | / | Unkown |
| HY-150595 | HDAC6-IN-10 | Inhibitor | / | Unkown |
| HY-174302 | PIM-1/HDAC-IN-2 | Inhibitor | / | Unkown |
| HY-179272 | Wee1/HDAC-IN-1 | Inhibitor | / | Unkown |
| HY-181579 | HDAC6-IN-74 | Inhibitor | / | Unkown |
| HY-169400 | HDACs/EZH2-IN-1 | Inhibitor | / | Unkown |
| HY-170379 | HDAC-IN-84 | Inhibitor | / | Unkown |
| HY-175030 | TNI-97 | Inhibitor | / | Unkown |
| HY-149283 | JAK/HDAC-IN-2 | Inhibitor | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service