HDAC11-IN-4
Based on 1 Customer Validation
HDAC11-IN-4 is a potent and selective HDAC11 inhibitor with an IC50 of 13.49 nM and a Ki of 2.2 nM. HDAC11-IN-4 exhibits extremely high selectivity for HDAC11 over other defatty-acylases such as SIRT2, SIRT3, SIRT6, and HDAC8 (SI >10,000). HDAC11-IN-4 can be used for the research of cancer.
For research use only. We do not sell to patients.
- Purity: 95.0%
- Formula: C26H49N5O4S
- Molecular Weight:527.76
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC11 13.49 nM (IC50) |
HDAC11 2.2 nM (Ki) |
Chemical Information
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Appearance Solid
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Molecular Weight 527.76
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Formula C26H49N5O4S
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Color White to off-white
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SMILES
CCCCCCCCCCCCSC[C@H](C(NCCCC[C@@H]1NC([C@@H](NC1=O)CCC(N)=O)=O)=O)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (189.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8948 mL | 9.4740 mL | 18.9480 mL | 47.3700 mL |
| 5 mM | 0.3790 mL | 1.8948 mL | 3.7896 mL | 9.4740 mL | |
| 10 mM | 0.1895 mL | 0.9474 mL | 1.8948 mL | 4.7370 mL | |
| 15 mM | 0.1263 mL | 0.6316 mL | 1.2632 mL | 3.1580 mL | |
| 20 mM | 0.0947 mL | 0.4737 mL | 0.9474 mL | 2.3685 mL | |
| 25 mM | 0.0758 mL | 0.3790 mL | 0.7579 mL | 1.8948 mL | |
| 30 mM | 0.0632 mL | 0.3158 mL | 0.6316 mL | 1.5790 mL | |
| 40 mM | 0.0474 mL | 0.2369 mL | 0.4737 mL | 1.1843 mL | |
| 50 mM | 0.0379 mL | 0.1895 mL | 0.3790 mL | 0.9474 mL | |
| 60 mM | 0.0316 mL | 0.1579 mL | 0.3158 mL | 0.7895 mL | |
| 80 mM | 0.0237 mL | 0.1184 mL | 0.2369 mL | 0.5921 mL | |
| 100 mM | 0.0189 mL | 0.0947 mL | 0.1895 mL | 0.4737 mL |
HDAC11-IN-4 Related Classifications
HY-178970 Related Classifications
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