HDAC11 - histone deacetylase 11 Gene

Also Known as HD11

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79885

About HDAC11

Cytogenetic location: 3p25.1 Genomic coordinates (GRCh38): 3:13,480,306-13,506,416 (from NCBI)

This gene has 21 transcripts (splice variants), 198 orthologues and 10 paralogues. Broad expression in brain (RPKM 17.4), testis (RPKM 14.8) and 22 other tissues.

Summary

This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009]

HDAC11 Products (3)

mRNA Protein Name
NM_001136041.3 NP_001129513.1 histone deacetylase 11 isoform 2
NM_001330636.2 NP_001317565.1 histone deacetylase 11 isoform 3
NM_024827.4 NP_079103.2 histone deacetylase 11 isoform 1

HDAC11 Protein Structure

Hist_deacetyl

Hist_deacetyl: Histone deacetylase domain (30 - 318)

  • 0
  • 100
  • 200
  • 300
  • 347 a.a.
Protein Preferred Names Protein Names

histone deacetylase 11

HDAC11 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83139 HDAC11 Antibody (YA2884) WB, IP Human

Related Diseases

Diseases Alias
Mature T-Cell And Nk-Cell Lymphoma

  • Mature T-Cell And Natural Killer Cell Lymphoma

  • Nk-T Cell Lymphoma
Peripheral T-Cell Lymphoma

  • Lymphoma T-Cell Peripheral
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10221 Vorinostat Inhibitor 99.96% Yes
HY-109015 Tucidinostat Inhibitor 98.74% Unkown
HY-12164 Mocetinostat Inhibitor 99.68% Yes
HY-14842 Givinostat Inhibitor 98.67% Yes
HY-13322 Pracinostat Inhibitor 99.80% Yes
HY-14842B Givinostat hydrochloride monohydrate Inhibitor 99.63% Yes
HY-14842A Givinostat hydrochloride Inhibitor 98.06% Yes

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-150109 Purinostat mesylate Inhibitor 99.45% Phase 3
HY-15433 Quisinostat Inhibitor 99.71% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-16012 Domatinostat tosylate Inhibitor 99.66% Phase 2

Pre-clinical Phase

Bioactive Molecules (59)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13428 Tubacin Inhibitor 98.71% Unkown
HY-18998 LMK-235 Inhibitor 99.61% Unkown
HY-112285 FT895 Inhibitor 99.84% Unkown
HY-128918 SIS17 Inhibitor 99.43% Unkown
HY-16699 Nexturastat A Inhibitor 98.69% Unkown
HY-145757 Elevenostat Inhibitor 95.07% Unkown
HY-15433A Quisinostat dihydrochloride Inhibitor 99.05% Unkown
HY-16012A Domatinostat Inhibitor 99.34% Unkown
HY-115475 SW-100 Inhibitor 99.93% Unkown
HY-126330 SS-208 Inhibitor 99.00% Unkown
HY-135714 Bavarostat Inhibitor 99.51% Unkown
HY-172157 HDAC11-IN-2 Inhibitor 99.52% Unkown
HY-176542 TD034 Inhibitor 99.77% Unkown
HY-143412 MIR002 Inhibitor 99.0% Unkown
HY-114483 AES-135 Inhibitor 98.68% Unkown
HY-143411 GEM144 Inhibitor / Unkown
HY-173444 HDAC11-IN-3 Inhibitor 99.70% Unkown
HY-110280 MC1742 Inhibitor 98.95% Unkown
HY-182019 HDAC11-IN-5 Inhibitor 98.25% Unkown
HY-138831 AES-350 Inhibitor 99.30% Unkown
HY-157740 XSJ-10 Inhibitor 95.16% Unkown
HY-178970 HDAC11-IN-4 Inhibitor 95.0% Unkown
HY-176868 Rodin-C Inhibitor / Unkown
HY-146684 HDAC-IN-36 Inhibitor / Unkown
HY-173076 HDAC11-IN-1 Inhibitor / Unkown
HY-161778 ZG-126 Inhibitor / Unkown
HY-157481 HDAC1-IN-6 Inhibitor / Unkown
HY-179019 HDAC-IN-94 Inhibitor / Unkown
HY-15144B (S)-Trichostatin A Inhibitor / Unkown
HY-152226 MC2590 Inhibitor 98.71% Unkown
HY-151263 G4/HDAC-IN-1 Inhibitor / Unkown
HY-152225 MC2625 Inhibitor / Unkown
HY-180811 ALK/HDAC-IN-2 Inhibitor / Unkown
HY-143877 NN-390 Inhibitor / Unkown
HY-159171 sEH/HDAC6-IN-2 Inhibitor / Unkown
HY-181579 HDAC6-IN-74 Inhibitor / Unkown
HY-184203 SM-06-09 Inhibitor / Unkown
HY-157889 ZINC000028464438 Inhibitor / Unkown
HY-181009 HDAC-IN-98 Inhibitor 98.36% Unkown
HY-163207 sEH/HDAC6-IN-1 Inhibitor / Unkown
HY-152173 HDAC-IN-51 Inhibitor / Unkown
HY-170379 HDAC-IN-84 Inhibitor / Unkown
HY-149283 JAK/HDAC-IN-2 Inhibitor / Unkown
HY-183560 HDAC6-IN-82 Inhibitor / Unkown
HY-182717 FT234 Inhibitor / Unkown
HY-161350 ALK/HDAC-IN-1 Inhibitor / Unkown
HY-162630 HDAC6-IN-44 Inhibitor / Unkown
HY-150772 Tubulin/HDAC-IN-1 Inhibitor / Unkown
HY-180214 HDAC6-IN-69 Inhibitor / Unkown
HY-147966 HDAC-IN-43 Inhibitor / Unkown
HY-184574 HDAC-IN-104 Inhibitor / Unkown
HY-162658 Leuxinostat Inhibitor / Unkown
HY-150595 HDAC6-IN-10 Inhibitor / Unkown
HY-174302 PIM-1/HDAC-IN-2 Inhibitor / Unkown
HY-163803 CM-444 Inhibitor / Unkown
HY-179272 Wee1/HDAC-IN-1 Inhibitor / Unkown
HY-15433B Quisinostat hydrochloride Inhibitor / Unkown
HY-169400 HDACs/EZH2-IN-1 Inhibitor / Unkown
HY-175030 TNI-97 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus HDAC11 MGD MGI:2385252
Canis familiaris HDAC11 VGNC VGNC:50627
Macaca mulatta HDAC11 VGNC VGNC:73196
Felis catus HDAC11 VGNC VGNC:62766
Bos taurus HDAC11 VGNC VGNC:49150
Rattus norvegicus HDAC11 RGD RGD:1311706
Others HDAC11 NCBI