1. Gene
  2. HDAC11 - histone deacetylase 11 Gene

HDAC11 - histone deacetylase 11 Gene

Homo sapiens

Also known as HD11

Gene ID: 79885 | Gene type: protein coding

About HDAC11

Cytogenetic location: 3p25.1 Genomic coordinates (GRCh38): 3:13,480,306-13,506,416 (from NCBI)

This gene has 21 transcripts (splice variants), 198 orthologues and 10 paralogues. Broad expression in brain (RPKM 17.4), testis (RPKM 14.8) and 22 other tissues.

Summary

This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009]

HDAC11 Products(3)

mRNA Protein Name
NM_001136041.3 NP_001129513.1 histone deacetylase 11 isoform 2
NM_001330636.2 NP_001317565.1 histone deacetylase 11 isoform 3
NM_024827.4 NP_079103.2 histone deacetylase 11 isoform 1

HDAC11 Protein Structure

Hist_deacetyl

Hist_deacetyl: Histone deacetylase domain (30 - 318)

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  • 347 a.a.
Protein Preferred Names Protein Names

histone deacetylase 11

Related Diseases

Diseases Alias
Mature T-Cell And Nk-Cell Lymphoma

Mature T-Cell And Natural Killer Cell Lymphoma

Nk-T Cell Lymphoma

Peripheral T-Cell Lymphoma

Lymphoma T-Cell Peripheral

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus HDAC11 MGD MGI:2385252
Canis familiaris HDAC11 VGNC VGNC:50627
Macaca mulatta HDAC11 VGNC VGNC:73196
Felis catus HDAC11 VGNC VGNC:62766
Bos taurus HDAC11 VGNC VGNC:49150
Rattus norvegicus HDAC11 RGD RGD:1311706