Leuxinostat
Leuxinostat is an inhibitor for HDAC with IC50 of 30 nM for hHDAC6. Leuxinostat inhibits the proliferation of cells THP1, K562, U937 and MEK1, induces apoptosis in leukemia cells NB4 and MOLT-4. Leuxinostat inhibits the expansion of hematopoietic stem cells and exhibits antileukemic activity in zebrafish models.
For research use only. We do not sell to patients.
- Formula: C18H20N4O4
- Molecular Weight:356.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
|
hHDAC6 0.03 μM (IC50) |
hHDAC1 1.203 μM (IC50) |
hHDAC8 2.446 μM (IC50) |
hHDAC3 2.858 μM (IC50) |
hHDAC10 4.811 μM (IC50) |
hHDAC11 5.57 μM (IC50) |
Chemical Information
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Molecular Weight 356.38
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Formula C18H20N4O4
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SMILES
O=C(NO)C(C=C1)=CC=C1CN2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Leuxinostat Related Classifications
HY-162658 Related Classifications
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