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Cat. No.: HY-157889

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ZINC000028464438

ZINC000028464438 is a selective HDAC11 inhibitor with an IC₅₀ of 3.5 µM. ZINC000028464438 shows almost no inhibition for other HDAC subtypes.

For research use only. We do not sell to patients.

CAS No.: 866123-66-2
Formula: C₂₁H₁₉N₃O₅
Molecular Weight:393.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

ZINC000028464438 Chemical Structure

CAS No.: 866123-66-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

ZINC000028464438 is a selective HDAC11 inhibitor with an IC₅₀ of 3.5 µM. ZINC000028464438 shows almost no inhibition for other HDAC subtypes^[1].

IC₅₀ & Target^[1]

HDAC11

3.5 μM (IC₅₀)

All HDAC Isoforms :

Chemical Information

CAS No. 866123-66-2
Molecular Weight 393.39
Formula C₂₁H₁₉N₃O₅
SMILES

COC1=C(C=C(C=C1)NC(C2=CC=CC(COC3=CC=CC=C3)=N2)=O)C(NO)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fady Baselious, et al. Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor. Int J Mol Sci. 2024 Jan 22;25(2):1358. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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ZINC000028464438

All HDAC Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ZINC000028464438 Related Classifications

HY-157889 Related Classifications