Slc8b1 - solute carrier family 8 member B1 Gene

Also Known as Slc24a6

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 498185

Summary

Enables protein homodimerization activity. Predicted to be involved in several processes, including cellular calcium ion homeostasis; regulation of Insulin secretion; and regulation of store-operated calcium entry. Predicted to act upstream of or within calcium ion transmembrane transport and sodium ion transmembrane transport. Located in mitochondrial crista and sarcolemma. Orthologous to human SLC8B1 (solute carrier family 8 member B1). [provided by Alliance of Genome Resources, Apr 2022]

Slc8b1 Products (1)

mRNA Protein Name
NM_001017488.1 NP_001017488.1 mitochondrial sodium/calcium exchanger protein precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IDA
IDA: Inferred from direct assay
20018762 RGD
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
20018762 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrial crista IDA
IDA: Inferred from direct assay
20018762 RGD
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
14625281 RGD
located in mitochondrion IDA
IDA: Inferred from direct assay
20018762 RGD
located in sarcolemma IDA
IDA: Inferred from direct assay
14625281 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial sodium/calcium exchanger protein

  • Na(+)/K(+)/Ca(2+)-exchange protein 6

  • sodium/calcium exchanger protein, mitochondrial

  • sodium/potassium/calcium exchanger 6, mitochondrial

  • solute carrier family 24 (sodium/lithium/calcium exchanger), member 6

  • solute carrier family 24 (sodium/potassium/c

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13340 SLC8B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20598 Slc8b1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27106 Slc8b1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc8b1 NCBI NCBI:80024