Prr7 - proline rich 7 (synaptic) Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 498704

Summary

Predicted to enable long-chain fatty acid binding activity; protein tyrosine kinase binding activity; and ubiquitin-like protein Ligase binding activity. Involved in negative regulation of protein ubiquitination and postsynapse to nucleus signaling pathway. Located in neuron projection; nucleus; and postsynaptic density. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Orthologous to human PRR7 (proline rich 7, synaptic). [provided by Alliance of Genome Resources, Apr 2022]

Prr7 Products (1)

mRNA Protein Name
NM_001109116.1 NP_001102586.1 proline-rich protein 7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27458189 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
27458189 RGD
Biological Process GO Annotation Evidence References Source
involved in postsynapse to nucleus signaling pathway IDA
IDA: Inferred from direct assay
27458189 RGD
involved in postsynapse to nucleus signaling pathway IMP
IMP: Inferred from mutant phenotype
27458189 RGD
involved in regulation of transcription by RNA polymerase I IMP
IMP: Inferred from mutant phenotype
27458189 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
15629447 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
15629447 RGD
located in neuron projection IDA
IDA: Inferred from direct assay
27458189 RGD
located in nucleus IDA
IDA: Inferred from direct assay
27458189 RGD
located in postsynaptic density IDA
IDA: Inferred from direct assay
27458189 RGD
is active in postsynaptic density, intracellular component IDA
IDA: Inferred from direct assay
15629447 RGD
is active in postsynaptic density, intracellular component IMP
IMP: Inferred from mutant phenotype
15629447 RGD
located in synapse IDA
IDA: Inferred from direct assay
27458189 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proline-rich protein 7

  • synaptic proline-rich membrane protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11233 PRR7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22288 Prr7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28811 Prr7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prr7 NCBI NCBI:80758