Sall2 - spalt like transcription factor 2 Gene

Also Known as Sal-2; Msal-2; mKIAA0360; p150(Sal2)

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50524

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within neural tube development. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; metanephros; neural ectoderm; reproductive system; and sensory organ. Human ortholog(s) of this gene implicated in coloboma. Orthologous to human SALL2 (spalt like transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sall2 Products (2)

mRNA Protein Name
NM_001244916.1 NP_001231845.1 sal-like protein 2 isoform 2
NM_015772.3 NP_056587.2 sal-like protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
16707490 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
16707490 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16707490 MGI
acts upstream of or within neural tube development IMP
IMP: Inferred from mutant phenotype
18818376 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sal-like protein 2

  • sal-like 2

  • spalt-like protein 2

  • zinc finger protein Spalt-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12418 SALL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21749 Sall2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28267 Sall2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sall2 NCBI NCBI:6297