Slc3a2 - solute carrier family 3 member 2 Gene

Also Known as Mdu1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 50567

Summary

Enables neutral amino acid transmembrane transporter activity. Involved in L-leucine import across plasma membrane. Located in apical plasma membrane and basal plasma membrane. Orthologous to human SLC3A2 (solute carrier family 3 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc3a2 Products (2)

mRNA Protein Name
NM_001271089.2 NP_001258018.1 4F2 cell-surface antigen heavy chain isoform 2
NM_019283.3 NP_062156.2 4F2 cell-surface antigen heavy chain isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables neutral L-amino acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
9480885 RGD
enables neutral L-amino acid transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
9726963 RGD
Biological Process GO Annotation Evidence References Source
involved in L-histidine transport IDA
IDA: Inferred from direct assay
10049700 RGD
involved in L-leucine import across plasma membrane IDA
IDA: Inferred from direct assay
9480885 RGD
involved in L-leucine transport IDA
IDA: Inferred from direct assay
9726963 RGD
involved in cellular response to glucose starvation IEP
IEP: Inferred from expression pattern
22185814 RGD
involved in neutral amino acid transport IMP
IMP: Inferred from mutant phenotype
9726963 RGD
involved in phenylalanine transport IDA
IDA: Inferred from direct assay
10049700 RGD
involved in response to muscle activity IEP
IEP: Inferred from expression pattern
24016666 RGD
involved in tryptophan transport IDA
IDA: Inferred from direct assay
10049700 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
11095508 RGD
located in basal plasma membrane IDA
IDA: Inferred from direct assay
11095508 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

4F2 cell-surface antigen heavy chain

  • 4F2hc

  • antigen identified by monoclonal antibodies 4F2

  • solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

  • solute carrier family 3 (amino acid transporter heavy chain), member 2

Recombinant Slc3a2 Proteins

Cat. No. Product Name Accession Purity
HY-P75663 CD98 Protein, Rat (HEK293, Fc) Q794F9 (A100-A527) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75664 CD98 Protein, Rat (HEK293, His) Q794F9 (A100-A527) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13242 SLC3A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16997 Slc3a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23440 Slc3a2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc3a2 NCBI NCBI:6520