Plaur - plasminogen activator, urokinase receptor Gene

Also Known as Par; uPAR; Plaur3; uPAR-2; uPAR-3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 50692

Summary

Predicted to enable enzyme binding activity; protein domain specific binding activity; and signaling receptor binding activity. Involved in several processes, including epithelial cell differentiation involved in prostate gland development; skeletal muscle tissue regeneration; and spermatogenesis. Predicted to be located in cell surface. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Biomarker of chronic obstructive pulmonary disease; myocardial infarction; and status epilepticus. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human PLAUR (plasminogen activator, urokinase receptor). [provided by Alliance of Genome Resources, Apr 2022]

Plaur Products (1)

mRNA Protein Name
NM_134352.2 NP_599179.2 urokinase plasminogen activator surface receptor precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in epithelial cell differentiation involved in prostate gland development IMP
IMP: Inferred from mutant phenotype
11798065 RGD
involved in mesenchymal cell differentiation IMP
IMP: Inferred from mutant phenotype
11798065 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
11798065 RGD
involved in skeletal muscle tissue regeneration IEP
IEP: Inferred from expression pattern
12919869 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
17712486 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urokinase plasminogen activator surface receptor

  • U-PAR

  • plasminogen activator urokinase receptor 3

  • urinary plasminogen activator receptor 2

  • urinary plasminogen activator receptor 3

  • urokinase plasminogen activator receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10648 PLAUR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17422 Plaur Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23877 Plaur Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plaur NCBI NCBI:5329