Fbxo6 - F-box protein 6 Gene

Also Known as FBG2; Fbs2; Fbx6b; Fbxo6b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50762

Summary

Enables carbohydrate binding activity. Contributes to ubiquitin protein Ligase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and ubiquitin-dependent ERAD pathway. Acts upstream of or within glycoprotein catabolic process. Located in endoplasmic reticulum quality control compartment. Part of SCF ubiquitin Ligase complex. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; liver; and lung. Orthologous to human FBXO6 (F-box protein 6). [provided by Alliance of Genome Resources, Apr 2022]

Fbxo6 Products (5)

mRNA Protein Name
NM_001163704.1 NP_001157176.1 F-box only protein 6
NM_001163705.1 NP_001157177.1 F-box only protein 6
NM_001163706.1 NP_001157178.1 F-box only protein 6
NM_001163707.1 NP_001157179.1 F-box only protein 6
NM_015797.4 NP_056612.1 F-box only protein 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables carbohydrate binding IDA
IDA: Inferred from direct assay
12939278 MGI
enables protein binding IDA
IDA: Inferred from direct assay
12939278 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15723043 MGI
contributes to ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
12939278 MGI
Biological Process GO Annotation Evidence References Source
involved in ERAD pathway IDA
IDA: Inferred from direct assay
21062743 MGI
involved in ERAD pathway IMP
IMP: Inferred from mutant phenotype
12939278 MGI
involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
12939278 MGI
acts upstream of or within glycoprotein catabolic process IDA
IDA: Inferred from direct assay
15723043 MGI
involved in ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
21062743 MGI
Cellular Component GO Annotation Evidence References Source
part of SCF ubiquitin ligase complex IDA
IDA: Inferred from direct assay
12939278 MGI
located in endoplasmic reticulum quality control compartment IDA
IDA: Inferred from direct assay
21062743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box only protein 6

  • F-box only protein 6b

  • F-box protein that recognizes sugar chains 2

  • F-box/G-domain protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04812 FBXO6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21571 Fbxo6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28089 Fbxo6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbxo6 NCBI NCBI:26270