Nt5c - 5',3'-nucleotidase, cytosolic Gene

Also Known as Dnt; Dnt1; Umph2; Umph-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50773

Summary

Enables IMP 5'-nucleotidase activity. Involved in allantoin metabolic process and nucleoside monophosphate catabolic process. Acts upstream of or within deoxyribonucleotide catabolic process. Located in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and thymus. Orthologous to human NT5C (5', 3'-nucleotidase, cytosolic). [provided by Alliance of Genome Resources, Apr 2022]

Nt5c Products (1)

mRNA Protein Name
NM_015807.1 NP_056622.1 5'(3')-deoxyribonucleotidase, cytosolic type

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 5'-nucleotidase activity IDA
IDA: Inferred from direct assay
6301357 MGI
enables IMP 5'-nucleotidase activity IDA
IDA: Inferred from direct assay
6301357 MGI
enables phosphatase activity IDA
IDA: Inferred from direct assay
1914521 MGI
Biological Process GO Annotation Evidence References Source
involved in IMP catabolic process IDA
IDA: Inferred from direct assay
6301357 MGI
involved in UMP catabolic process IDA
IDA: Inferred from direct assay
10681516 MGI
involved in allantoin metabolic process IDA
IDA: Inferred from direct assay
6301357 MGI
involved in amide catabolic process IDA
IDA: Inferred from direct assay
6301357 MGI
involved in dCMP catabolic process IDA
IDA: Inferred from direct assay
6301357 MGI
involved in dGMP catabolic process IDA
IDA: Inferred from direct assay
10681516 MGI
involved in dTMP catabolic process IDA
IDA: Inferred from direct assay
6301357 MGI
involved in dUMP catabolic process IDA
IDA: Inferred from direct assay
10681516 MGI
acts upstream of or within deoxyribonucleotide catabolic process IDA
IDA: Inferred from direct assay
10681516 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
10681516 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5'(3')-deoxyribonucleotidase, cytosolic type

  • 5' nucleotidase, deoxy (pyrimidine), cytosolic type C

  • cytosolic 5',3'-pyrimidine nucleotidase

  • dNT-1

  • deoxy-5'-nucleotidase 1

  • uridine monophosphatase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-167710 CRCD2 99.02% Unkown
HY-RS09607 NT5C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09608 NT5C1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09609 NT5C2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16401 NT5C3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19266 Nt5c1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21396 Nt5c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21673 Nt5c2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25755 Nt5c1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27683 Nt5c3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27915 Nt5c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28191 Nt5c2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nt5c NCBI NCBI:30833