NUSAP1 - nucleolar and spindle associated protein 1 Gene

Also Known as LNP; ANKT; SAPL; BM037; NUSAP; Q0310; PRO0310p1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51203

About NUSAP1

Cytogenetic location: 15q15.1 Genomic coordinates (GRCh38): 15:41,332,881-41,381,046 (from NCBI)

This gene has 14 transcripts (splice variants) and 205 orthologues. Broad expression in bone marrow (RPKM 30.9), lymph node (RPKM 16.8) and 15 other tissues.

Summary

NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et al., 2003 [PubMed 12963707]).[supplied by OMIM, Jun 2009]

NUSAP1 Products (6)

mRNA Protein Name
NM_001243142.2 NP_001230071.1 nucleolar and spindle-associated protein 1 isoform 4
NM_001243143.2 NP_001230072.1 nucleolar and spindle-associated protein 1 isoform 5
NM_001243144.2 NP_001230073.1 nucleolar and spindle-associated protein 1 isoform 6
NM_001301136.2 NP_001288065.1 nucleolar and spindle-associated protein 1 isoform 7
NM_016359.5 NP_057443.2 nucleolar and spindle-associated protein 1 isoform 1
NM_018454.8 NP_060924.4 nucleolar and spindle-associated protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within establishment of mitotic spindle localization IDA
IDA: Inferred from direct assay
12963707 GOA
acts upstream of or within mitotic chromosome condensation IDA
IDA: Inferred from direct assay
12963707 GOA
acts upstream of or within mitotic cytokinesis IDA
IDA: Inferred from direct assay
12963707 GOA
acts upstream of or within mitotic sister chromatid segregation IDA
IDA: Inferred from direct assay
12963707 GOA
acts upstream of or within positive regulation of mitotic nuclear division IDA
IDA: Inferred from direct assay
12963707 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleolar and spindle-associated protein 1

  • nucleolar protein ANKT

Related Diseases

Diseases Alias
Microcephaly, Seizures, And Developmental Delay

  • MCSZ

  • Developmental And Epileptic Encephalopathy 10

  • Epileptic Encephalopathy, Early Infantile, 10

  • Eiee10

  • Dee10

  • Early Infantile Epileptic Encephalopathy 10
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09704 NUSAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20573 Nusap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27081 Nusap1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NUSAP1 VGNC VGNC:32370
Canis familiaris NUSAP1 VGNC VGNC:44067
Rattus norvegicus NUSAP1 RGD RGD:1305764
Felis catus NUSAP1 VGNC VGNC:63932
Macaca mulatta NUSAP1 VGNC VGNC:75431
Mus musculus NUSAP1 MGD MGI:2675669
Others NUSAP1 NCBI