GOLM1 - golgi membrane protein 1 Gene

Also Known as GP73; HEL46; GOLPH2; C9orf155; PSEC0257; bA379P1.3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51280

About GOLM1

Cytogenetic location: 9q21.33 Genomic coordinates (GRCh38): 9:86,026,146-86,100,149 (from NCBI)

This gene has 8 transcripts (splice variants), 195 orthologues and 1 paralogue. Broad expression in stomach (RPKM 210.4), colon (RPKM 117.5) and 14 other tissues.

Summary

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral Infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Sep 2009]

GOLM1 Products (2)

mRNA Protein Name
NM_016548.4 NP_057632.2 Golgi membrane protein 1
NM_177937.3 NP_808800.1 Golgi membrane protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
21280149 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Golgi membrane protein 1

  • epididymis luminal protein 46

GOLM1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
GOLM1 Q8NBJ4 SLC30A3 Homo sapiens Q99726
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 SLC35B2 Homo sapiens Q8TB61
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 TMEM109 Homo sapiens Q9BVC6
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 TMUB1 Homo sapiens Q9BVT8
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 AIG1 Homo sapiens Q9NVV5-2
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 CLDND2 Homo sapiens Q8NHS1
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 SLC5A4 Homo sapiens Q9NY91
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 ST6GAL2 Homo sapiens Q96JF0-2
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 SLCO3A1 Homo sapiens Q9UIG8-2
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
Intra
GOLM1 Q8NBJ4 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
Intra
GOLM1 Q8NBJ4 TMEM176A Homo sapiens Q96HP8
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 NINJ1 Homo sapiens Q92982
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 CNPY3 Homo sapiens Q9BT09
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 TMEM140 Homo sapiens Q9NV12
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 EGFR Homo sapiens P00533
Anti Bait CoIP
27569582
Intra
GOLM1 Q8NBJ4 EGFR Homo sapiens P00533
Anti Tag CoIP
27569582
Intra
GOLM1 Q8NBJ4 EGFR Homo sapiens P00533
Confocal
27569582
Intra
GOLM1 Q8NBJ4 EGFR Homo sapiens P00533
Pull Down
27569582
Intra
GOLM1 Q8NBJ4 THSD7A Homo sapiens Q9UPZ6
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 TSG101 Homo sapiens Q99816
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 TMEM147 Homo sapiens Q9BVK8
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 FUT9 Homo sapiens Q9Y231
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 NDUFV2 Homo sapiens P19404
Y2H Prey Pooling
32296183
Intra
GOLM1 Q8NBJ4 NDUFV2 Homo sapiens P19404
Y2H Array
32296183
Intra
GOLM1 Q8NBJ4 NEU1 Homo sapiens Q99519
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 TMEM98 Homo sapiens Q9Y2Y6
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 ABI3 Homo sapiens Q9P2A4
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 INSIG2 Homo sapiens Q9Y5U4
Validated Y2H
32296183
Intra
GOLM1 Q8NBJ4 INSIG2 Homo sapiens Q9Y5U4
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant GOLM1 Proteins

Cat. No. Nom du produit Accession Pureté
HY-P70879 GOLM1 Protein, Human (HEK293, His) Q8NBJ4-1 (S36-L401) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72209 GOLM1 Protein, Human (His) Q8NBJ4-1 (S36-L401) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P72209A GOLM1 Protein, Human (His, Solution) Q8NBJ4-1 (S36-L401) ≥ 95%, as determined by reducing SDS-PAGE.

GOLM1 Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P83002 GOLPH2 Antibody (YA2747) WB, IHC-P, ICC/IF, FC Human, Mouse, Rat

Related Diseases

Diseases Alias
Autoimmune Hepatitis

  • Aih

  • Hepatitis, Autoimmune

  • Autoimmune Chronic Active Hepatitis

  • Autoimmune Hepatitis With Centrilobular Necrosis

  • Autoimmune Chronic Hepatitis

  • Hepatitis Autoimmune
Liver Disease

  • Liver Failure

  • Liver Diseases

  • Abnormality Of The Liver

  • Liver Dysfunction

  • Disorder Of Liver

  • Hepatic Disorder

  • Hepatic Disease

  • Disease Of Bilirubin Metabolism

  • Disorder Of Bilirubin Metabolism

  • Liver Decompensation

  • Liver Function Failure

  • Hepatic Failure Nos

  • Liver Failure Nos

  • End Stage Liver Disease

  • Decompensated Liver Failure

  • Decompensation Of Liver Function

  • Hepatic Decompensation

  • Hepatic Insufficiency

  • Liver Cell Necrosis With Hepatic Failure

  • Liver Insufficiency

  • Decompensated Liver Disease

  • End Stage Liver Failure

  • Liver Necrosis With Hepatic Failure
Hepatitis

  • Chronic Hepatitis

  • Chronic Persistent Hepatitis

  • Acute Hepatitis

  • Hepatitis, Chronic

  • Acute And Subacute Liver Necrosis

  • Acute/Subac. Necrosis Of Liver

  • Animal Hepatitis

  • Hepatitis Chronic

  • Hepatitis A

  • Hepatitis, Animal

  • Hepatitis Due To Toxoplasmosis

  • Hepatitis In Toxoplasmosis

  • Toxoplasmal Hepatitis

  • Chronic Hepatitis, Unspecified

  • Chronic Active Hepatitis Nec

  • Other Specified Chronic Hepatitis

  • Chronic Persistent Hepatitis Nec

  • Chronic Lobular Hepatitis Nec
Wilson Disease

  • Hepatolenticular Degeneration

  • WD

  • Wilson'S Disease

  • WND

  • Westphal-Strumpell Syndrome

  • Copper Storage Disease

  • Cerebral Pseudosclerosis

  • Westphal Pseudosclerosis

  • Hepatolenticular Degeneration Syndrome

  • Copper Retention

  • Hepatocerebral Degeneration

  • Kinnier-Wilson Disease

  • Neurohepatic Degeneration

  • Progressive Hepatolenticular Degeneration

  • Lenticular Degenerative Disease

  • Wilson'S Syndrome

  • Lenticular Syndrome
Spinocerebellar Ataxia 44

  • SCA44
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS05592 GOLM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19437 Golm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25928 Golm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P990421 Anti-GOLM1 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GOLM1 VGNC VGNC:41345
Mus musculus GOLM1 MGD MGI:1917329
Rattus norvegicus GOLM1 RGD RGD:1589384
Macaca mulatta GOLM1 VGNC VGNC:72946
Felis catus GOLM1 VGNC VGNC:62643
Bos taurus GOLM1 VGNC VGNC:29491
Others GOLM1 NCBI