TMUB1 - transmembrane and ubiquitin like domain containing 1 Gene

Also Known as DULP; HOPS; SB144; C7orf21

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83590

Summary

Involved in ERAD pathway. Predicted to be located in several cellular components, including centrosome; postsynaptic membrane; and recycling endosome. Predicted to be active in postsynaptic recycling endosome membrane. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in colon (RPKM 10.6), kidney (RPKM 10.4) and 25 other tissues.

TMUB1 Products (2)

mRNA Protein Name
NM_001136044.2 NP_001129516.1 transmembrane and ubiquitin-like domain-containing protein 1
NM_031434.4 NP_113622.1 transmembrane and ubiquitin-like domain-containing protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
21343306 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in ERAD pathway IMP
IMP: Inferred from mutant phenotype
21343306 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMUB1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
TMUB1 Q9BVT8 AMFR Homo sapiens Q9UKV5
Anti Tag CoIP
21343306
Intra
TMUB1 Q9BVT8 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
Intra
TMUB1 Q9BVT8 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
Intra
TMUB1 Q9BVT8 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
Intra
TMUB1 Q9BVT8 ERLIN2 Homo sapiens O94905
Anti Tag CoIP
21343306
Intra
TMUB1 Q9BVT8 ERLIN2 Homo sapiens O94905
Anti Tag CoIP
33961781
Intra
TMUB1 Q9BVT8 GOLM1 Homo sapiens Q8NBJ4
Y2H Array
32296183
Intra
TMUB1 Q9BVT8 GOLM1 Homo sapiens Q8NBJ4
Y2H Prey Pooling
32296183
Intra
TMUB1 Q9BVT8 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
Intra
TMUB1 Q9BVT8 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
Intra
TMUB1 Q9BVT8 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra
TMUB1 Q9BVT8 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra
TMUB1 Q9BVT8 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS15128 TRUB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown