TMEM176A - transmembrane protein 176A Gene

Homo sapiens

Also known as GS188; MS4B1; HCA112

Gene ID: 55365 | Gene type: protein coding

About TMEM176A

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:150,800,769-150,805,118 (from NCBI)

This gene has 11 transcripts (splice variants), 86 orthologues and 1 paralogue. Broad expression in liver (RPKM 172.7), kidney (RPKM 114.0) and 15 other tissues.

Summary

Predicted to be involved in negative regulation of dendritic cell differentiation. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM176A Products(1)

mRNA	Protein	Name
NM_018487.3	NP_060957.2	transmembrane protein 176A

TMEM176A Protein Structure

CD20

0
100
200
235 a.a.

Protein Preferred Names

Protein Names

transmembrane protein 176A

hepatocellular carcinoma-associated antigen 112

Related Diseases

Diseases

Alias

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14684	TMEM176A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TMEM176A	VGNC	VGNC:66292
Rattus norvegicus	TMEM176A	RGD	RGD:1310725
Mus musculus	TMEM176A	MGD	MGI:1913308
Canis familiaris	TMEM176A	VGNC	VGNC:47501
Bos taurus	TMEM176A	VGNC	VGNC:36000
Macaca mulatta	TMEM176A	VGNC	VGNC:81774

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