1. Gene
  2. CPVL - carboxypeptidase vitellogenic like Gene

CPVL - carboxypeptidase vitellogenic like Gene

Homo sapiens

Also known as HVLP

Gene ID: 54504 | Gene type: protein coding

About CPVL

Cytogenetic location: 7p14.3 Genomic coordinates (GRCh38): 7:28,994,636-29,195,451 (from NCBI)

This gene has 12 transcripts (splice variants), 193 orthologues and 2 paralogues. Broad expression in spleen (RPKM 87.7), thyroid (RPKM 67.4) and 23 other tissues.

Summary

The protein encoded by this gene is a Carboxypeptidase and bears strong sequence similarity to serine carboxypeptidases. Carboxypeptidases are a large class of proteases that act to cleave a single amino acid from the carboxy termini of proteins or Peptides. The exact function of this protein, however, has not been determined. [provided by RefSeq, Jan 2017]

CPVL Products(17)

mRNA Protein Name
NM_001348052.1 NP_001334981.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001348054.1 NP_001334983.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001371255.1 NP_001358184.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001371256.1 NP_001358185.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001371257.1 NP_001358186.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001371258.1 NP_001358187.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001371260.1 NP_001358189.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001371261.1 NP_001358190.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001371262.1 NP_001358191.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001371263.1 NP_001358192.1 probable serine carboxypeptidase CPVL isoform b precursor
NM_001371264.1 NP_001358193.1 probable serine carboxypeptidase CPVL isoform a precursor
NM_001371265.1 NP_001358194.1 probable serine carboxypeptidase CPVL isoform c
NM_001371266.1 NP_001358195.1 probable serine carboxypeptidase CPVL isoform c
NM_001371267.1 NP_001358196.1 probable serine carboxypeptidase CPVL isoform c
NM_001371268.1 NP_001358197.1 probable serine carboxypeptidase CPVL isoform d
NM_019029.3 NP_061902.2 probable serine carboxypeptidase CPVL isoform b precursor
NM_031311.5 NP_112601.3 probable serine carboxypeptidase CPVL isoform b precursor

CPVL Protein Structure

Peptidase_S10

Peptidase_S10: Serine carboxypeptidase (69 - 467)

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  • 476 a.a.
Protein Preferred Names Protein Names

probable serine carboxypeptidase CPVL

CP-Mac carboxypeptidase

Recombinant CPVL Proteins

Cat. No. Product Name Accession Purity
HY-P7818 CPVL Protein, Human (HEK293, His) AAH16838.1 (L23-G476) ≥95%

Related Diseases

Diseases Alias
Noonan Syndrome 6

NS6

Noonan Syndrome, Type 6

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus CPVL VGNC VGNC:58370
Macaca mulatta CPVL VGNC VGNC:71406
Mus musculus CPVL MGD MGI:1918537
Canis familiaris CPVL VGNC VGNC:39584
Felis catus CPVL VGNC VGNC:61150
Rattus norvegicus CPVL RGD RGD:1563609
Others CPVL NCBI