2. Gene
  3. EPB41L4B - erythrocyte membrane protein band 4.1 like 4B Gene

EPB41L4B - erythrocyte membrane protein band 4.1 like 4B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CG1; EHM2; LULU2

Gene ID: 54566 | Gene type: protein coding

About EPB41L4B

Cytogenetic location: 9q31.3 Genomic coordinates (GRCh38): 9:109,171,974-109,321,059 (from NCBI)

This gene has 2 transcripts (splice variants), 200 orthologues and 10 paralogues. Broad expression in colon (RPKM 20.8), thyroid (RPKM 15.3) and 18 other tissues.

Summary

Predicted to be a structural constituent of Cytoskeleton. Involved in several processes, including positive regulation of cell adhesion; positive regulation of keratinocyte migration; and wound healing. Acts upstream of or within actomyosin structure organization. Located in apical part of cell; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EPB41L4B Products(3)

mRNA Protein Name
NM_001385623.1 NP_001372552.1 band 4.1-like protein 4B isoform 3
NM_018424.3 NP_060894.2 band 4.1-like protein 4B isoform 1
NM_019114.5 NP_061987.3 band 4.1-like protein 4B isoform 2

EPB41L4B Protein Structure

FERM_N

FERM_N: FERM N-terminal domain (89 - 165)

FERM_M

FERM_M: FERM central domain (169 - 277)

FERM_C

FERM_C: FERM C-terminal PH-like domain (283 - 370)

FA

FA: FERM adjacent (FA) (378 - 421)

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Protein Preferred Names Protein Names

band 4.1-like protein 4B

FERM-containing protein CG1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04415 EPB41L4B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus EPB41L4B VGNC VGNC:28524
Felis catus EPB41L4B VGNC VGNC:61896
Mus musculus EPB41L4B MGD MGI:1859149
Canis familiaris EPB41L4B VGNC VGNC:40397
Macaca mulatta EPB41L4B VGNC VGNC:103260
Rattus norvegicus EPB41L4B RGD RGD:1562988