MINDY2 - MINDY lysine 48 deubiquitinase 2 Gene

Also Known as FAM63B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54629

About MINDY2

Cytogenetic location: 15q21.3-q22.1 Genomic coordinates (GRCh38): 15:58,771,302-58,861,900 (from NCBI)

This gene has 5 transcripts (splice variants), 209 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 6.3), fat (RPKM 6.3) and 25 other tissues.

Summary

Enables cysteine-type peptidase activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in protein K48-linked deubiquitination. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MINDY2 Products (2)

mRNA Protein Name
NM_001040450.3 NP_001035540.1 ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform a
NM_001040453.3 NP_001035543.1 ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform b

MINDY2 Protein Structure

MINDY_DUB

MINDY_DUB: MINDY deubiquitinase (272 - 397)

  • 0
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  • 500
  • 621 a.a.
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase MINDY-2

  • MINDY deubiquitinase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08452 MINDY2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MINDY2 VGNC VGNC:63511
Rattus norvegicus MINDY2 RGD RGD:1311456
Canis familiaris MINDY2 VGNC VGNC:43237
Mus musculus MINDY2 MGD MGI:2443086
Bos taurus MINDY2 VGNC VGNC:31477
Macaca mulatta MINDY2 VGNC VGNC:74838
Others MINDY2 NCBI