MINDY2 - MINDY lysine 48 deubiquitinase 2 Gene

Homo sapiens

Also known as FAM63B

Gene ID: 54629 | Gene type: protein coding

About MINDY2

Cytogenetic location: 15q21.3-q22.1 Genomic coordinates (GRCh38): 15:58,771,302-58,861,900 (from NCBI)

This gene has 5 transcripts (splice variants), 209 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 6.3), fat (RPKM 6.3) and 25 other tissues.

Summary

Enables cysteine-type peptidase activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in protein K48-linked deubiquitination. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MINDY2 Products(2)

mRNA	Protein	Name
NM_001040450.3	NP_001035540.1	ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform a
NM_001040453.3	NP_001035543.1	ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform b

MINDY2 Protein Structure

MINDY_DUB

0
100
200
300
400
500
621 a.a.

Protein Preferred Names

Protein Names

ubiquitin carboxyl-terminal hydrolase MINDY-2

MINDY deubiquitinase 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08452	MINDY2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MINDY2	VGNC	VGNC:63511
Rattus norvegicus	MINDY2	RGD	RGD:1311456
Canis familiaris	MINDY2	VGNC	VGNC:43237
Mus musculus	MINDY2	MGD	MGI:2443086
Bos taurus	MINDY2	VGNC	VGNC:31477
Macaca mulatta	MINDY2	VGNC	VGNC:74838

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