TMEM214 - transmembrane protein 214 Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 54867

About TMEM214

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,032,965-27,041,694 (from NCBI)

This gene has 13 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in placenta (RPKM 25.1), thyroid (RPKM 23.8) and 25 other tissues.

Summary

Predicted to be involved in apoptotic process. Located in several cellular components, including Golgi apparatus; cytoplasmic microtubule; and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

TMEM214 Products (2)

mRNA	Protein	Name
NM_001083590.2	NP_001077059.1	transmembrane protein 214 isoform 2
NM_017727.5	NP_060197.4	transmembrane protein 214 isoform 1

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	References	Source
located in cytoplasmic microtubule	IDA IDA: Inferred from direct assay	23264731	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM214 Protein Structure

TMEM214

0
200
400
600
689 a.a.

Protein Preferred Names	Protein Names
transmembrane protein 214

Related Diseases

Diseases	Alias
Myopathy, X-Linked, With Postural Muscle Atrophy	Emery-Dreifuss Muscular Dystrophy 6, X-Linked XMPMA X-Linked Myopathy With Postural Muscle Atrophy X-Linked Emery-Dreifuss Muscular Dystrophy 6 EDMD6 Emd6
Emery-Dreifuss Muscular Dystrophy 7, Autosomal Dominant	EDMD7 Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 7 Emery-Dreifuss Muscular Dystrophy 7, Ad Emd7 Dystrophy, Muscular, Emery-Dreifuss, Type 7, Autosomal Dominant
Emery-Dreifuss Muscular Dystrophy 5, Autosomal Dominant	EDMD5 Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 5 Emd5 Dystrophy, Muscular, Emery-Dreifuss, Type 5, Autosomal Dominant
Emery-Dreifuss Muscular Dystrophy 4, Autosomal Dominant	EDMD4 Emery-Dreifuss Muscular Dystrophy 4 With Variable Features Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 4 Emd4 Dystrophy, Muscular, Emery-Dreifuss, Type 4, Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 4

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14698	TMEM214 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TMEM214	VGNC	VGNC:36036
Rattus norvegicus	TMEM214	RGD	RGD:1311324
Macaca mulatta	TMEM214	VGNC	VGNC:103879
Canis familiaris	TMEM214	VGNC	VGNC:47532
Mus musculus	TMEM214	MGD	MGI:1916046
Felis catus	TMEM214	VGNC	VGNC:66311
Others	TMEM214	NCBI