GALNT10 - polypeptide N-acetylgalactosaminyltransferase 10 Gene

Also Known as GALNACT10; PPGALNACT10; PPGANTASE10

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55568

About GALNT10

Cytogenetic location: 5q33.2 Genomic coordinates (GRCh38): 5:154,190,733-154,420,984 (from NCBI)

This gene has 10 transcripts (splice variants), 261 orthologues and 19 paralogues. Ubiquitous expression in ovary (RPKM 33.6), gall bladder (RPKM 12.6) and 23 other tissues.

Summary

This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These Enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010]

GALNT10 Products (1)

mRNA Protein Name
NM_198321.4 NP_938080.1 polypeptide N-acetylgalactosaminyltransferase 10

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables polypeptide N-acetylgalactosaminyltransferase activity IDA
IDA: Inferred from direct assay
12417297 GOA
Biological Process GO Annotation Evidence References Source
involved in O-glycan processing IDA
IDA: Inferred from direct assay
18562306 GOA
involved in protein O-linked glycosylation IDA
IDA: Inferred from direct assay
12417297 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GALNT10 Protein Structure

Glycos_transf_2

Glycos_transf_2: Glycosyl transferase family 2 (148 - 332)

Ricin_B_lectin

Ricin_B_lectin: Ricin-type beta-trefoil lectin domain (459 - 587)

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  • 603 a.a.
Protein Preferred Names Protein Names

polypeptide N-acetylgalactosaminyltransferase 10

  • GalNAc transferase 10

Recombinant GALNT10 Proteins

Cat. No. Product Name Accession Purity
HY-P76354 GALNT10 Protein, Human (HEK293, His) Q86SR1-1/NP_938080.1 (T39-N603) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05248 GALNT10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21237 Galnt10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27754 Galnt10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GALNT10 VGNC VGNC:41085
Rattus norvegicus GALNT10 RGD RGD:69409
Bos taurus GALNT10 VGNC VGNC:29223
Felis catus GALNT10 VGNC VGNC:97442
Mus musculus GALNT10 MGD MGI:1890480
Macaca mulatta GALNT10 VGNC VGNC:72748
Others GALNT10 NCBI