ZNF692 - zinc finger protein 692 Gene

Also Known as AREBP; Zfp692

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55657

About ZNF692

Cytogenetic location: 1q44 Genomic coordinates (GRCh38): 1:248,850,008-248,859,085 (from NCBI)

This gene has 30 transcripts (splice variants), 135 orthologues and 36 paralogues. Ubiquitous expression in testis (RPKM 9.4), prostate (RPKM 7.1) and 25 other tissues.

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and regulation of gluconeogenesis. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZNF692 Products (5)

mRNA Protein Name
NM_001136036.3 NP_001129508.1 zinc finger protein 692 isoform 1
NM_001193328.2 NP_001180257.1 zinc finger protein 692 isoform 3
NM_001350072.2 NP_001337001.1 zinc finger protein 692 isoform 4
NM_001350073.2 NP_001337002.1 zinc finger protein 692 isoform 5
NM_017865.4 NP_060335.2 zinc finger protein 692 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
17097062 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
17097062 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17097062 GOA
involved in regulation of gluconeogenesis IMP
IMP: Inferred from mutant phenotype
21910974 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF692 Protein Structure

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (329 - 350)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (359 - 383)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (403 - 426)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (448 - 471)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 519 a.a.
Protein Preferred Names Protein Names

zinc finger protein 692

  • AICAR responsive element binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16166 ZNF692 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZNF692 MGD MGI:2144276
Macaca mulatta ZNF692 VGNC VGNC:100195
Canis familiaris ZNF692 VGNC VGNC:48797
Bos taurus ZNF692 VGNC VGNC:37330
Felis catus ZNF692 VGNC VGNC:102371
Rattus norvegicus ZNF692 RGD RGD:1306740
Others ZNF692 NCBI