PRR11 - proline rich 11 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55771

About PRR11

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:59,155,746-59,206,709 (from NCBI)

This gene has 9 transcripts (splice variants), 136 orthologues and 2 paralogues. Broad expression in bone marrow (RPKM 3.3), lymph node (RPKM 2.7) and 20 other tissues.

Summary

Involved in regulation of cell cycle. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PRR11 Products (1)

mRNA Protein Name
NM_018304.4 NP_060774.2 proline-rich protein 11

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of cell cycle IDA
IDA: Inferred from direct assay
23246489 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
23246489 GOA
located in nucleus IDA
IDA: Inferred from direct assay
23246489 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proline-rich protein 11

  • transcription repressor of MHCII

Related Diseases

Diseases Alias
Klatskin'S Tumor

  • Klatskin Tumor

  • Hilar Cholangiocarcinoma

  • Perihilar Cholangiocarcinoma

  • Hilar Cholangiocellular Carcinoma

  • Klatskin Tumour

  • Klatskin'S Tumour

  • Perihilar Extrahepatic Bile Duct Carcinoma

  • Hilar Cca

  • Adenocarcinoma Of Hepatic Duct

  • Klatskin Tumour Of Biliary Tree
Mulibrey Nanism

  • MUL

  • Muscle-Liver-Brain-Eye Nanism

  • Pericardial Constriction And Growth Failure

  • Perheentupa Syndrome

  • Mulibrey Growth Disorder

  • Mulibrey Nanism Syndrome

  • Pericardial Constriction With Growth Failure

  • Nanism Mulibrey
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11222 PRR11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PRR11 VGNC VGNC:64380
Canis familiaris PRR11 VGNC VGNC:45036
Mus musculus PRR11 MGD MGI:2444496
Macaca mulatta PRR11 VGNC VGNC:76316
Rattus norvegicus PRR11 RGD RGD:1561541
Bos taurus PRR11 VGNC VGNC:33388
Others PRR11 NCBI